Learn where to find accurate patent expiration dates in the FDA Orange Book to predict when generic drugs will become available. Includes step-by-step search tips, common pitfalls, and how to interpret patent and exclusivity data.
learn moreGeneric substitution was meant to lower drug costs, but flawed reimbursement models now benefit PBMs more than patients or pharmacies. Learn how MAC lists, spread pricing, and dispensing fees shape who really saves money.
learn moreGovernment controls generic drug prices in the U.S. through rebates, Medicare negotiation, and safety-net programs - not direct price-setting. Learn how Medicaid, 340B, and the Inflation Reduction Act shape what you pay at the pharmacy.
learn moreGeneric drugs may contain the same active ingredient as brand-name versions, but differences in formulation and packaging can lead to faster degradation. Understanding stability testing and shelf life is critical for safety and effectiveness.
learn moreEsketamine nasal spray (Spravato) offers rapid relief for treatment-resistant depression but comes with strict monitoring due to dissociation and blood pressure spikes. Learn how it works, what to expect, and why safety protocols matter.
learn moreParoxetine can cause significant weight gain over time, especially after 6 months of use. Learn why it happens, how much weight people typically gain, and what you can do to manage or reverse it - including safer alternatives and proven lifestyle strategies.
learn moreGeneric and brand-name drugs contain the same active ingredient and carry the same risk of drug interactions. Scientific evidence confirms their safety and equivalence, with only rare exceptions tied to inactive ingredients.
learn moreGene therapy offers hope for genetic diseases but brings hidden risks when combined with other drugs. Immune reactions, delayed side effects, and unpredictable drug metabolism make safety a long-term challenge.
learn moreThe DSCSA track-and-trace system is the U.S. government's nationwide effort to stop counterfeit drugs by requiring every prescription package to have a unique digital identifier. Here's how it works, who it affects, and why it matters for patient safety.
learn moreInsurers save billions on generic drugs by using bulk buying and tendering to force down prices through competitive bidding. Learn how it works, why some generics still cost too much, and how you can save too.
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